Katherine Woodville (c. 1458 – 18 May 1497) was an English medieval noblewoman. She was the sister-in-law of King Edward IV of England and gave birth to several illustrious children. Catherine was the daughter of Richard Woodville, 1st Earl Rivers, and Jacquetta of Luxembourg. When her sister Elizabeth Woodville married King Edward IV, the King elevated and promoted many members of the Woodville family.
Sometime before the coronation of Elizabeth in May 1465, Catherine was married to Henry Stafford, 2nd Duke of Buckingham; both were still children. A contemporary description of Elizabeth Woodville's coronation relates that Catherine and her husband were carried on squires' shoulders due to their youth. According to Dominic Mancini, Buckingham resented his marriage to a woman of lower status. However, the couple had four children.