King Henry is stunned by a reversal in his alliance with Emperor Charles and forced to look elsewhere for European support, while Anne Boleyn refuses his offer of mistress status, inflaming his desire to marry her. Katherine of Aragon's alliance with Charles and her hatred for Cardinal Wolsey intensify. Wolsey urges appealing to Clement VII because the English bishops don't all approve of annulling Henry's marriage to Catherine. Charles Brandon and the newly-widowed Margaret Tudor marry secretly, which infuriates the King, and he banishes both of them from court. Henry bestows a Dukedom on his bastard son Henry FitzRoy, but is heartbroken when FitzRoy dies only weeks later. Rome is sacked by Charles V.